Ionis Pharmaceuticals, Inc IONS

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Ionis Pharmaceuticals, Inc. - Common Stock · Company · Nasdaq · Healthcare / Biotechnology

Paper trade (simulated — no real money)

Fill: USD 42.9300 · FX 1 USD = 1.277900 SGD · about SGD 54.8602 per unit

Sign in to practise with simulated trades before investing real money. USD fills are converted into the SGD portfolio at the displayed rate.

Announcement types: (default: consequential filings)
Results & current reports
Capital markets
Ownership & governance

USD closing-price chart (daily close from yfinance · Last year)

USD 70.86 → 42.93 · -39.4%
86.50064.44042.380 1,2 3 4 5 6 7 8 9 10 11 12,13 14,15 16 17 18 19 20 21 22,23 24,25 26 27 Oct 25Jan 26Apr 26Jul 26Oct 26

Numbered dotted lines mark the filtered filings under Announcement Events below.

Price & SEC Filing History 24 Oct 2025 — 25 Oct 2026 (Last year)

Daily Nasdaq prices are sourced from yfinance. Yellow highlighting marks an intraday rise or a gap up between adjacent trading sessions. SEC acceptance times are converted to US Eastern time: pre-market filings appear below that day’s OHLCV row; filings accepted after the 09:30 ET open appear above it. The SEC does not publish an exact first-public-availability timestamp, so acceptance time is the best available proxy.

Weekend
Weekend
43.8000 43.8000 42.6150 42.9300 3,013,739
45.0200 45.1500 43.4100 43.9100 5,012,000
27 · 8-K After-hours · 20:15 ET 8-K ↗
45.5500 45.7600 44.2600 44.2700 2,268,100
44.4500 45.4800 44.0100 45.4000 2,486,600
43.3300 44.5400 43.0000 44.3800 3,098,900
Weekend
Weekend
44.5300 44.6500 42.8000 42.9400 1,674,800
43.5800 44.7100 43.4200 44.1200 2,484,800
42.2200 43.4700 42.0800 42.7000 2,027,200
43.5500 43.5800 42.3600 42.3800 2,977,600
45.3700 45.4600 43.6200 43.6700 1,950,400
Weekend
Weekend
43.2100 45.7200 43.1200 45.2800 4,862,000
43.7600 44.1900 42.7900 43.3000 3,349,200
43.7500 44.2600 43.5300 44.1600 2,943,600
44.1900 44.6700 43.1700 44.0000 2,192,600
43.7500 43.9600 42.6300 43.5000 2,870,600
Weekend
Weekend
44.1700 44.1700 43.2400 43.5400 2,312,000
44.6300 45.9500 43.9600 44.0000 2,030,200
46.0700 46.2500 44.6000 44.6500 2,630,200
45.5300 46.4600 45.3900 45.8900 3,885,800
44.5600 46.9500 44.0600 45.5700 3,742,300
Weekend
Weekend
44.2500 45.2800 43.6200 44.5000 6,202,100
43.7700 44.6000 43.2500 43.8100 6,448,100
46.2300 46.4100 43.0100 43.9300 3,535,300
26 · 8-K Pre-market · 06:03 ET CURRENT REPORT FILING ↗
44.9600 46.1300 44.4400 45.7500 4,230,800
44.9500 45.2500 44.2000 44.9000 4,520,700
Weekend
Weekend
46.7500 46.7500 44.2700 44.4400 7,369,000
46.6800 47.4200 45.7500 46.7500 4,079,600
47.3800 47.5900 44.6600 44.8400 7,956,400
51.3700 51.3700 46.7200 47.2500 6,812,100
54.8800 55.5000 51.3100 51.4400 5,974,800
Weekend
Weekend
55.9400 56.1600 54.1600 54.2100 2,175,700
55.7500 55.7700 54.9100 55.6500 3,057,300
56.3800 56.9600 55.7000 56.0200 3,037,000
52.1500 57.4300 52.1500 56.7100 9,175,700
No trading
Weekend
Weekend
25 · 8-K After-hours · 17:00 ET 8-K ↗
58.3600 58.9600 57.7800 58.0900 2,671,100
24 · 8-K Pre-market · 06:01 ET 8-K ↗
60.4200 60.4200 57.4700 58.1300 4,343,700
60.2500 61.7700 59.7800 61.3300 1,845,200
60.3700 60.9900 59.7800 59.8800 1,872,600
61.0700 61.0700 59.7000 60.3600 2,017,100
Weekend
Weekend
60.6200 61.6900 60.3500 61.0500 1,850,900
63.4800 63.4800 62.3400 62.4300 1,625,200
63.5000 63.5500 62.4400 63.3600 2,152,200
62.5300 64.1900 62.1900 63.5700 2,432,000
60.5400 62.0700 59.7000 62.0400 2,206,900
Weekend
Weekend
59.6400 60.9200 59.0600 59.7400 2,723,500
60.0300 60.4100 58.6000 58.7600 2,124,800
60.1100 61.3600 59.6100 60.8000 3,137,600
58.4100 60.1900 58.0200 59.6200 3,192,500
57.1100 58.7400 56.4100 58.6300 2,000,200
Weekend
Weekend
55.1600 57.2400 55.1600 57.2400 1,353,700
56.5000 56.8100 55.5600 55.8700 1,220,400
55.0100 57.0700 54.9100 56.5300 1,999,700
56.7900 57.1600 55.3700 55.4200 2,406,900
56.1000 57.6600 56.1000 56.9400 2,399,800
Weekend
Weekend
54.7300 56.6000 54.4000 56.5600 2,009,200
54.5900 55.4200 54.0200 54.4900 2,592,300
55.1700 55.3600 53.5800 54.1900 2,122,300
54.8500 55.2200 53.8700 55.0700 2,688,200
52.6600 54.5400 52.1700 54.4900 3,212,600
Weekend
Weekend
53.3300 53.3300 51.2800 51.7700 2,570,500
53.9200 54.0400 52.6500 53.2800 2,875,000
22 · 10-Q After-hours · 17:05 ET IONIS PHARMACEUTICALS, INC. 10-Q 06-30-2026 ↗
55.0900 55.3600 53.5000 54.0400 3,129,200
23 · 8-K Pre-market · 07:31 ET 8-K ↗
56.5600 56.5600 54.0000 55.3000 2,804,600
56.9300 57.0900 55.7900 55.9600 2,584,700
Weekend
Weekend
56.3200 57.3600 56.1900 56.5500 3,094,700
53.7100 57.4800 53.3500 55.8700 3,834,300
51.1600 54.0600 50.0100 54.0100 8,732,700
52.7500 54.1300 52.2600 53.3900 3,074,000
54.4700 54.8000 52.8200 52.9500 2,166,900
Weekend
Weekend
54.1000 54.6900 53.7600 54.3900 2,572,800
53.9500 55.9800 53.3800 54.6500 3,805,300
54.4800 54.8900 53.5100 54.7300 3,577,100
55.8000 56.4600 54.5300 54.9300 4,700,000
57.9100 57.9100 56.1100 56.7500 5,097,900
Weekend
Weekend
64.2700 64.4400 58.2000 58.2500 11,444,100
21 · 8-K Next filing day · accepted 09 Jul, 21:03 ET 8-K ↗ 20 · 8-K After market open · 14:55 ET 8-K ↗
67.7800 70.3500 64.1000 64.2700 20,447,600
85.5600 86.7400 83.9200 84.4600 2,280,800
84.4200 86.6700 82.9500 86.3300 2,646,700
82.1100 84.0100 81.1900 83.1800 1,847,400
Weekend
Weekend
No trading
79.5300 81.9900 79.1100 81.8000 2,301,700
79.1300 79.4800 77.9500 79.1900 1,442,400
81.1700 81.2400 79.2100 79.2900 2,380,300
81.0000 82.5300 79.9500 80.6900 2,806,600
Weekend
Weekend
78.8000 82.6300 78.8000 81.1800 3,828,200
76.6900 79.5500 76.2500 78.3400 2,583,200
19 · 8-K After market open · 15:48 ET 8-K ↗
76.4000 79.0000 76.0400 76.5200 2,485,700
75.8900 77.3100 75.7700 75.9900 1,405,400
74.8500 76.5600 74.1200 75.8900 1,956,100
Weekend
Weekend
No trading
75.0000 75.6600 73.5000 74.1200 2,984,400
73.0900 75.1200 72.5500 74.3100 1,788,200
73.9300 73.9600 72.3000 73.0900 1,801,400
73.4900 74.2700 72.8800 73.9600 1,506,300
Weekend
Weekend
18 · 8-K After market open · 14:20 ET 8-K ↗
73.8200 74.3500 72.5700 73.2800 1,964,900
73.3400 74.4800 72.7600 73.8200 2,234,400
74.4300 75.8500 72.8300 73.3200 1,595,700
74.7700 75.7900 73.5300 74.5800 1,568,700
17 · 8-K After market open · 12:49 ET 8-K ↗
74.3300 74.4300 73.1400 73.5400 1,620,700
Weekend
Weekend
75.2400 75.9600 73.8100 74.4800 1,982,000
74.0100 75.8800 73.8200 75.1300 1,240,800
72.6800 74.1200 72.0200 73.8200 1,303,900
74.8500 75.2300 72.5600 72.9700 2,086,200
75.6700 76.1900 74.7000 75.3800 1,467,700
Weekend
Weekend
77.5400 78.1000 76.3900 76.5000 1,675,600
16 · 8-K After market open · 12:41 ET 8-K ↗
76.5800 78.0000 75.3400 77.3300 1,603,000
76.2400 77.4000 76.2300 76.4900 1,341,300
76.0000 76.7400 74.7300 76.0700 1,279,200
No trading
Weekend
Weekend
75.7100 76.8000 75.0000 75.5600 1,579,200
74.7600 76.4800 74.2100 75.7800 2,295,200
74.6700 75.6900 73.9700 75.0600 2,005,300
72.7600 74.1500 72.0000 73.8400 1,519,500
74.5800 74.7900 71.9300 72.5200 2,211,500
Weekend
Weekend
75.8900 75.9300 73.3200 74.2300 2,119,200
79.0000 79.1900 75.3100 75.6800 1,798,300
75.6700 78.0300 75.0800 77.6000 1,360,300
76.0300 77.1300 75.3800 75.8300 1,408,900
76.0300 77.0100 74.8500 75.3800 1,533,700
Weekend
Weekend
76.4500 77.4000 75.2400 75.7100 1,656,200
76.5600 76.5600 74.8700 76.0200 1,885,700
75.6200 77.4200 75.2900 76.8500 1,799,900
75.8400 76.9600 74.8200 75.2500 850,200
75.2800 76.0000 74.4700 75.4500 1,689,400
Weekend
Weekend
74.8600 76.1700 72.9400 75.2800 1,821,500
74.9100 77.7600 73.8100 74.7600 2,430,300
14 · 10-Q After market open · 14:33 ET IONIS PHARMACEUTICALS, INC. 10-Q 03-31-2026 ↗
72.0600 74.9600 71.3000 74.8300 3,675,200
15 · 8-K Pre-market · 07:00 ET 8-K ↗
72.7100 73.1000 71.1800 71.7800 2,396,300
74.0400 75.1000 72.2100 72.2300 2,311,600
Weekend
Weekend
74.0900 74.5100 72.3300 73.2700 1,817,400
13 · DEFA14A After-hours · 16:22 ET DEFA14A ↗ 12 · DEF 14A After-hours · 16:21 ET DEF 14A ↗
74.9600 76.0600 73.2300 74.0900 1,377,400
75.2200 75.4400 74.0000 74.8300 2,024,000
75.8700 75.9600 73.8000 74.7800 1,818,800
11 · 8-K Pre-market · 07:00 ET 8-K ↗
75.5000 75.6200 74.5800 74.8700 1,106,800
Weekend
Weekend
75.6600 76.3300 74.9500 75.7100 1,719,400
76.4200 76.5300 73.9100 75.2600 1,873,900
77.1000 77.1800 75.7700 76.8200 1,288,400
74.8800 77.3800 74.8800 76.7600 1,595,300
75.1700 77.1700 74.5600 74.9500 1,650,900
Weekend
Weekend
77.0200 77.1500 74.5300 75.1700 1,581,600
74.9800 76.9700 74.6200 76.4300 1,201,000
76.0700 76.4800 74.3000 74.9800 1,266,700
74.0500 74.2700 72.4200 73.8900 1,118,300
74.5400 75.4800 73.5600 74.3300 1,440,900
Weekend
Weekend
No trading
73.7400 75.1300 73.3500 74.7900 1,791,600
75.7000 76.4800 74.7900 75.1300 1,665,000
73.6400 75.9200 73.4500 75.0900 1,852,300
73.1200 73.2100 71.4800 72.5200 2,045,500
Weekend
Weekend
74.0000 74.0500 71.8700 72.1500 1,948,400
72.2500 75.6300 70.5000 74.2400 3,884,000
70.6800 73.6100 70.6800 72.7000 2,994,300
70.2700 70.6400 68.9000 69.6800 1,844,400
72.2500 73.1500 70.6700 70.7900 2,198,100
Weekend
Weekend
71.5100 72.5900 70.5000 70.9900 2,920,600
71.4000 71.9400 70.5100 71.3200 2,247,900
71.8400 72.3000 70.9200 71.6700 2,180,300
72.3500 73.3000 71.9200 72.3300 1,985,000
71.5800 72.8800 71.2900 72.3400 3,231,500
Weekend
Weekend
73.2100 74.1600 70.4200 71.1900 1,972,100
74.3000 74.3000 72.0100 72.3400 2,461,800
75.1500 76.0000 74.5400 74.7900 1,895,400
75.3600 77.0300 74.5100 75.6600 2,785,700
73.5000 75.6300 73.4500 75.3600 3,215,200
10 · 8-K Pre-market · 07:00 ET 8-K ↗
Weekend
Weekend
73.9700 75.1600 73.1500 74.0400 1,904,100
78.1600 79.0400 74.2700 75.1600 2,969,700
79.1600 80.0700 77.6700 79.4500 2,503,100
80.4200 81.4000 78.5000 78.6600 2,045,100
79.2700 82.7500 79.2700 81.9600 3,098,400
Weekend
Weekend
80.5900 82.1000 80.0600 81.1500 2,773,700
9 · 10-K After-hours · 16:25 ET IONIS PHARMACEUTICALS, INC. 10-K 12-31-2025 ↗
80.3200 82.4400 78.9200 80.6000 3,330,000
81.7500 85.1200 80.4700 80.9300 3,188,700
8 · 8-K Pre-market · 07:00 ET 8-K ↗
84.6600 85.4700 83.4500 85.4500 2,384,800
82.7100 84.9600 82.7100 84.6000 1,724,200
Weekend
Weekend
82.8500 83.6300 81.6400 83.1500 2,832,500
81.5000 83.3400 80.3900 83.1500 2,024,000
81.2600 83.0600 80.9800 82.2200 1,949,800
80.3000 82.5300 80.2300 81.3600 1,889,500
No trading
Weekend
Weekend
81.1800 82.5600 79.7800 80.6000 1,931,200
84.2000 84.9100 81.2000 81.7800 1,734,700
84.1900 84.9600 82.0000 84.3500 1,104,200
84.4900 84.8100 83.5700 84.2900 1,382,700
86.1300 86.4900 84.6100 84.7900 1,738,100
Weekend
Weekend
84.8500 86.5900 84.1800 86.5000 1,996,500
84.5100 86.7400 82.8900 83.4800 2,677,700
85.7200 85.9500 82.5500 84.9900 3,009,900
83.0000 85.4500 83.0000 84.5900 1,461,100
82.5400 83.3500 81.9000 83.0700 1,788,900
Weekend
Weekend
83.4800 83.7000 82.2100 82.6700 2,518,400
82.3800 84.3000 81.9000 83.8800 1,646,700
81.9200 82.6300 81.6300 81.9200 1,732,400
81.0100 82.5200 81.0100 82.1400 2,338,600
79.4900 81.2800 79.2400 81.0000 1,700,600
Weekend
Weekend
81.7100 82.2000 79.1100 80.2900 2,128,900
79.6200 82.1900 78.8900 81.7900 3,695,400
77.0900 79.5400 77.0100 79.4400 3,298,700
75.0300 77.9900 74.2000 77.5300 4,894,300
No trading
Weekend
Weekend
77.1500 78.0000 74.4900 76.3300 3,000,600
79.2500 79.7500 77.1500 77.2100 1,408,900
79.0400 79.5700 77.6900 78.8700 2,121,500
82.2400 82.5700 78.6100 79.4800 1,885,200
80.5000 82.2100 78.8800 81.6600 1,570,500
7 · 8-K Pre-market · 07:00 ET 8-K ↗
Weekend
Weekend
82.1700 83.2300 79.3000 80.3000 2,668,600
83.1700 83.7900 79.9500 81.5400 2,051,500
82.5000 86.1500 82.4000 83.1700 3,889,400
6 · 8-K Pre-market · 06:02 ET 8-K ↗
78.8900 81.5400 78.0000 81.4900 2,651,700
79.1800 79.4200 76.0800 78.5300 1,448,700
Weekend
Weekend
79.8800 80.2100 78.0200 79.6700 1,400,400
No trading
78.7800 79.8400 78.6300 79.1100 1,096,900
79.5000 79.9900 78.5200 78.9700 1,146,100
79.7300 80.0400 78.7400 79.9800 1,077,900
Weekend
Weekend
80.1500 80.4200 79.1800 79.9300 725,300
No trading
80.3300 81.0200 80.3300 80.6500 480,200
80.6100 81.8400 79.6300 80.3300 1,229,900
79.2600 82.0900 79.0900 81.3400 2,257,800
Weekend
Weekend
77.8000 79.8300 77.6300 79.5700 3,557,500
77.3900 78.1600 76.7000 77.6300 1,765,600
78.7700 79.4900 77.0700 77.0800 2,145,800
79.4100 79.5600 77.1600 78.3700 1,959,700
80.3500 81.0000 79.3100 79.7600 1,977,600
Weekend
Weekend
79.1900 80.9200 78.5100 80.8200 1,468,900
78.6300 79.8600 78.0500 79.1400 2,052,200
79.3800 79.7100 77.7900 78.6300 2,659,300
80.5500 81.2300 78.3200 78.8600 1,866,200
82.1200 82.8600 81.1800 81.5100 1,553,600
Weekend
Weekend
82.1900 82.4400 80.6400 81.6800 1,715,000
81.9000 83.6100 81.4500 81.8100 2,317,800
81.7000 83.0900 80.9800 81.8400 2,531,200
82.3800 82.6900 80.0000 81.3100 2,454,600
82.0300 82.2700 80.1100 81.9900 1,865,400
Weekend
Weekend
82.5900 82.9500 81.6700 82.7300 852,900
No trading
81.1500 82.9100 80.7500 82.7000 2,955,400
78.5200 81.2000 78.3300 80.9300 2,543,000
76.3400 78.7900 76.1600 78.5200 3,217,000
Weekend
Weekend
73.0000 76.3100 73.0000 76.0900 2,075,900
74.1700 75.4000 72.5000 73.1200 3,208,800
74.5500 75.0000 71.8300 74.0000 3,620,800
72.8100 74.5200 71.9900 74.5000 2,056,700
5 · 8-K After-hours · 16:06 ET 8-K ↗
70.7000 74.4200 70.7000 73.2600 3,504,600
Weekend
Weekend
69.6600 72.5400 68.9000 71.5500 3,372,300
72.5600 73.0500 68.2200 69.8400 11,502,700
71.1900 74.5000 70.4000 72.6700 5,067,900
69.3200 72.7900 68.5500 72.4500 2,268,600
70.0500 71.4900 66.6600 69.5400 4,399,700
4 · 8-K Pre-market · 06:04 ET 8-K ↗
Weekend
Weekend
73.5800 75.0000 72.3600 73.5500 2,332,300
74.5800 76.7800 73.9100 74.1000 2,424,200
72.1400 75.0800 71.4800 74.6800 2,259,100
72.4000 74.2100 72.4000 72.8800 1,726,300
3 · 8-K/A After-hours · 17:17 ET 8-K/A ↗
74.7700 75.2500 71.9500 73.6500 2,576,000
Weekend
Weekend
74.5000 75.4900 74.0200 74.3000 2,395,600
71.9100 74.7000 71.6600 74.1700 2,177,600
1 · 10-Q After-hours · 16:43 ET IONIS PHARMACEUTICALS, INC. 10-Q 9-30-2025 ↗
72.3700 74.0500 71.1400 71.8800 2,164,200
2 · 8-K Pre-market · 07:06 ET 8-K ↗
72.9900 74.0400 72.5000 73.5700 2,559,600
72.0300 73.2700 71.4600 72.9900 1,842,500
Weekend
Weekend
72.3900 72.4400 70.2200 70.8600 1,990,300

Announcement Events

Each title opens the filing on the SEC website. Registered users can summarise the filing and up to seven relevant exhibits linked within the same SEC submission.

27 8-K 8-K (opens SEC filing in a new tab) After-hours · 20:15 ET Summarise
26 8-K CURRENT REPORT FILING (opens SEC filing in a new tab) Pre-market · 06:03 ET Summarise
25 8-K 8-K (opens SEC filing in a new tab) After-hours · 17:00 ET Summarise
24 8-K 8-K (opens SEC filing in a new tab) Pre-market · 06:01 ET Summarise
23 8-K 8-K (opens SEC filing in a new tab) Pre-market · 07:31 ET Summarise
22 10-Q IONIS PHARMACEUTICALS, INC. 10-Q 06-30-2026 (opens SEC filing in a new tab) After-hours · 17:05 ET Summarise
21 8-K 8-K (opens SEC filing in a new tab) Next filing day · accepted 09 Jul, 21:03 ET Summarise
20 8-K 8-K (opens SEC filing in a new tab) After market open · 14:55 ET Summarise
19 8-K 8-K (opens SEC filing in a new tab) After market open · 15:48 ET Summarise
18 8-K 8-K (opens SEC filing in a new tab) After market open · 14:20 ET Summarise
17 8-K 8-K (opens SEC filing in a new tab) After market open · 12:49 ET Summarise
16 8-K 8-K (opens SEC filing in a new tab) After market open · 12:41 ET Summarise
15 8-K 8-K (opens SEC filing in a new tab) Pre-market · 07:00 ET Summarise
14 10-Q IONIS PHARMACEUTICALS, INC. 10-Q 03-31-2026 (opens SEC filing in a new tab) After market open · 14:33 ET Summarise
13 DEFA14A DEFA14A (opens SEC filing in a new tab) After-hours · 16:22 ET Summarise
12 DEF 14A DEF 14A (opens SEC filing in a new tab) After-hours · 16:21 ET Summarise
11 8-K 8-K (opens SEC filing in a new tab) Pre-market · 07:00 ET Summarise
10 8-K 8-K (opens SEC filing in a new tab) Pre-market · 07:00 ET Summarise
9 10-K IONIS PHARMACEUTICALS, INC. 10-K 12-31-2025 (opens SEC filing in a new tab) After-hours · 16:25 ET Summarise
8 8-K 8-K (opens SEC filing in a new tab) Pre-market · 07:00 ET Summarise
7 8-K 8-K (opens SEC filing in a new tab) Pre-market · 07:00 ET Summarise
6 8-K 8-K (opens SEC filing in a new tab) Pre-market · 06:02 ET Summarise
5 8-K 8-K (opens SEC filing in a new tab) After-hours · 16:06 ET Summarise
4 8-K 8-K (opens SEC filing in a new tab) Pre-market · 06:04 ET Summarise
3 8-K/A 8-K/A (opens SEC filing in a new tab) After-hours · 17:17 ET Summarise
2 8-K 8-K (opens SEC filing in a new tab) Pre-market · 07:06 ET Summarise
1 10-Q IONIS PHARMACEUTICALS, INC. 10-Q 9-30-2025 (opens SEC filing in a new tab) After-hours · 16:43 ET Summarise