Upstream Bio, Inc UPB

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Upstream Bio, Inc. - Common Stock · Company · Nasdaq

Paper trade (simulated — no real money)

Fill: USD 6.4100 · FX 1 USD = 1.289800 SGD · about SGD 8.2676 per unit

Sign in to place simulated trades. USD fills are converted into the SGD portfolio at the displayed rate.

Announcement types: (default: consequential filings)
Results & current reports
Capital markets
Ownership & governance

USD closing-price chart (daily close from yfinance · Last year)

USD 14.34 → 6.41 · -55.3%
32.60019.2605.920 1,2 3 4,5,6 7,8 9,10,11,12 13,14 15,16 17 Jul 25Oct 25Jan 26Apr 26Jul 26

Numbered dotted lines mark the filtered filings under Announcement Events below.

Price & SEC Filing History 26 Jul 2025 — 27 Jul 2026 (Last year)

Daily Nasdaq prices are sourced from yfinance. Yellow highlighting marks an intraday rise or a gap up between adjacent trading sessions. SEC acceptance times are converted to US Eastern time: pre-market filings appear below that day’s OHLCV row; filings accepted after the 09:30 ET open appear above it. The SEC does not publish an exact first-public-availability timestamp, so acceptance time is the best available proxy.

No data yet
Weekend
Weekend
6.4000 6.6100 6.1600 6.4100 626,400
6.4600 6.5900 6.3200 6.4000 626,100
6.9500 6.9900 6.4700 6.5900 704,500
6.9200 7.0800 6.8600 6.9800 341,000
6.9900 7.1450 6.8000 6.9800 458,000
Weekend
Weekend
7.0800 7.3000 6.9000 7.0100 378,000
7.2400 7.3400 6.9800 7.2300 561,200
7.1200 7.3200 7.0800 7.2700 332,100
7.2800 7.3400 7.0000 7.1400 344,700
7.4700 7.5250 7.0200 7.2800 266,100
Weekend
Weekend
7.8100 7.8100 7.2800 7.5300 341,700
7.9800 8.0000 7.5700 7.8100 467,500
7.7300 8.0000 7.5300 7.9800 635,100
7.4800 8.0000 7.3200 7.8600 809,500
7.5000 7.5910 7.3400 7.4000 357,000
Weekend
Weekend
No trading
7.3100 7.7200 7.1640 7.5100 363,200
6.9000 7.4200 6.8100 7.2800 561,000
6.9400 7.3800 6.8800 6.9200 557,800
6.7700 7.0000 6.5600 6.9300 662,700
Weekend
Weekend
6.3600 6.7800 6.3500 6.7500 1,311,200
6.3200 6.5700 6.2800 6.3600 469,900
6.3500 6.7100 6.3200 6.3500 654,600
6.2600 6.5400 6.2400 6.3200 623,900
6.3300 6.6000 6.2500 6.3000 849,200
Weekend
Weekend
No trading
6.2600 6.5200 6.1450 6.2500 829,700
5.9400 6.3300 5.8800 6.1500 839,800
6.1000 6.1850 5.8600 5.9200 519,900
6.1900 6.2800 6.0100 6.1000 681,400
Weekend
Weekend
6.0300 6.4700 5.8500 6.1000 1,432,200
6.2800 6.4000 6.1100 6.3800 833,100
17 · 8-K After-hours · 16:05 ET 8-K ↗
6.6400 6.8010 6.2500 6.2800 450,100
6.5300 6.7800 6.4150 6.6900 500,500
7.1600 7.1600 6.4050 6.4500 783,900
Weekend
Weekend
7.3900 7.4500 6.9800 7.0500 672,400
7.6800 7.7800 7.3000 7.4300 688,200
7.5200 7.8600 7.4000 7.6300 666,400
7.9600 7.9600 7.1850 7.2500 632,600
8.3300 8.6400 7.9900 8.0800 595,100
Weekend
Weekend
8.3100 8.5000 8.1650 8.3600 499,100
8.2400 8.3750 8.1300 8.3200 320,800
8.1900 8.5500 8.1850 8.2600 420,400
8.4400 8.4500 8.1050 8.2100 593,000
No trading
Weekend
Weekend
8.4700 8.6900 8.3300 8.3700 354,400
8.3500 8.5950 8.2500 8.4600 597,500
8.0200 8.5600 7.9900 8.4100 593,000
8.4200 8.6400 8.0200 8.0300 982,500
8.9700 9.1300 8.1240 8.5100 511,300
Weekend
Weekend
8.5900 9.1400 8.5500 9.0900 979,900
9.4500 9.5180 8.5050 8.7900 568,800
8.9600 9.4650 8.8000 9.3600 815,600
16 · 10-Q Pre-market · 07:10 ET 10-Q ↗ 15 · 8-K Pre-market · 07:05 ET 8-K ↗
8.9300 9.1400 8.8300 8.9500 467,500
9.2000 9.5950 9.0500 9.1100 618,900
Weekend
Weekend
8.8800 9.3500 8.8000 9.0900 456,000
9.1400 9.1400 8.6900 8.9850 272,800
9.1600 9.2900 8.9800 9.1900 409,200
9.3100 9.5000 8.8800 9.1200 262,700
9.3400 9.5700 9.1600 9.3100 300,400
Weekend
Weekend
9.2500 9.4100 9.1200 9.4000 489,700
9.2000 9.3000 9.0600 9.1800 395,000
9.3200 9.3700 8.9700 9.1900 415,800
9.3200 9.6450 9.2800 9.5100 474,600
9.2200 9.6350 9.1530 9.2900 664,700
Weekend
Weekend
9.4700 9.6300 9.2100 9.3000 558,800
9.6200 9.7200 9.3800 9.6000 428,000
9.3100 9.7050 9.0600 9.6400 624,800
10.0100 10.0530 9.2200 9.2600 527,000
9.9800 10.0900 9.7900 9.9900 387,900
Weekend
Weekend
10.4500 10.6400 9.8350 9.9900 661,400
14 · DEFA14A After-hours · 16:10 ET DEFA14A ↗ 13 · DEF 14A After-hours · 16:05 ET DEF 14A ↗
9.8800 10.1500 9.6800 10.1000 1,152,800
10.4000 10.5200 9.7900 9.8800 552,100
10.1350 10.4500 10.0770 10.3400 645,900
10.4500 10.6050 10.0900 10.2300 412,500
Weekend
Weekend
10.4800 10.6680 10.3350 10.4900 733,100
9.6700 10.4900 9.6300 10.4200 813,000
9.8700 10.0000 9.4520 9.8400 474,400
9.5900 9.7050 9.3100 9.7000 316,800
9.4900 9.8900 9.3640 9.7200 502,200
Weekend
Weekend
No trading
9.0600 9.6400 8.9650 9.5000 537,600
9.2200 9.3500 8.9600 9.3100 848,800
9.0100 9.1700 8.8200 9.0000 1,034,600
8.5300 8.7800 8.2900 8.7800 863,200
Weekend
Weekend
8.7200 9.1500 8.1000 8.6700 939,900
12 · 8-K After-hours · 17:09 ET 8-K ↗ 11 · 424B5 After-hours · 17:05 ET 424B5 ↗ 10 · 10-K After-hours · 16:04 ET 10-K ↗
9.4800 10.4300 9.3800 9.7900 883,200
9 · 8-K Pre-market · 07:05 ET 8-K ↗
8.6800 9.5700 8.6700 9.4700 687,000
8.3500 8.6200 8.1200 8.4500 747,600
8.7100 9.0300 8.4300 8.4500 743,400
Weekend
Weekend
8.3800 8.6800 8.1630 8.6700 3,024,900
8.4400 8.6300 8.2300 8.3800 734,900
9.5800 9.7000 8.6550 8.6650 719,600
9.5800 9.9000 9.1700 9.7100 914,800
9.2900 9.6750 9.2700 9.6100 722,500
Weekend
Weekend
9.3200 9.7600 8.9300 9.2300 723,100
9.2700 9.4700 8.7000 9.4350 1,135,900
8.1600 9.3700 8.1600 9.3600 1,691,500
8.1500 8.3600 7.9900 8.1200 653,700
7.6500 8.0900 7.6400 8.0600 1,194,300
Weekend
Weekend
7.4700 7.7700 7.4000 7.6600 702,500
7.6400 7.7800 7.4000 7.6700 941,700
7.3700 8.0100 7.3330 7.8000 1,170,500
7.5850 7.6400 7.2500 7.3600 998,200
7.5100 7.9150 7.4600 7.7000 1,672,700
Weekend
Weekend
7.8700 8.0700 7.6200 7.6800 1,436,000
7.7400 8.3170 7.7000 7.9000 1,497,000
7.9000 8.1000 7.7000 7.7400 987,800
8.0500 8.2700 7.7800 7.9200 1,538,700
8.0900 8.3200 7.7400 8.0200 1,625,500
Weekend
Weekend
8.4100 8.6900 8.0100 8.0800 3,594,900
8.3200 8.7270 8.1400 8.5400 1,924,100
8.1800 8.6600 7.9300 8.2900 2,893,200
8.6850 9.0000 7.9600 8.3300 6,026,000
No trading
Weekend
Weekend
12.6900 12.6900 8.5200 8.7500 6,503,600
14.8600 14.8600 12.7500 12.8000 3,879,100
19.0000 20.0100 12.6500 14.6900 8,848,200
8 · 8-K Pre-market · 09:17 ET 8-K ↗ 7 · 8-K Pre-market · 06:38 ET 8-K ↗
26.1000 28.5750 25.9300 27.8100 800,800
26.2400 26.2400 25.1600 26.1200 509,700
Weekend
Weekend
26.5600 27.9800 25.9400 26.2000 517,900
29.4000 30.3100 25.8700 26.0000 619,300
30.8800 30.8800 28.3450 29.3800 610,500
30.3800 31.0500 29.8200 30.7900 635,700
31.1000 32.3810 29.6400 29.9400 783,100
Weekend
Weekend
30.6400 31.3700 29.7100 31.0800 667,500
30.3000 31.1150 29.6100 30.9400 459,600
32.5000 32.5000 29.9900 30.4300 658,100
30.2400 32.8300 30.1300 32.5000 1,068,800
29.7700 30.9100 29.7600 30.1600 545,700
Weekend
Weekend
31.6200 31.6200 29.8250 30.0200 371,100
31.7400 32.5200 31.7040 31.7900 402,500
30.9500 32.1400 30.3100 31.5900 468,400
30.2200 31.5200 29.0800 31.0000 774,100
No trading
Weekend
Weekend
31.0600 31.6400 29.8000 31.0000 418,400
32.4200 32.4200 30.7400 30.9000 718,900
32.6800 33.6800 31.9500 32.3000 621,000
31.7100 32.6600 30.4800 32.6000 834,700
29.7300 31.9300 29.3400 31.6600 679,000
Weekend
Weekend
27.8700 30.6000 27.8700 29.7500 851,400
27.7100 28.4900 27.2150 27.5400 502,700
26.0800 28.1600 26.0800 28.0800 700,300
25.9300 26.5200 25.0000 25.8700 452,800
27.0700 27.3900 25.2500 26.1300 689,800
Weekend
Weekend
27.3000 28.0100 26.7200 27.0700 586,400
No trading
27.1700 27.5800 26.8600 27.1500 517,800
28.7700 28.7700 26.8550 27.3200 831,500
29.4800 29.9200 28.7000 28.8300 238,300
Weekend
Weekend
30.1100 30.1100 29.1000 29.4800 228,000
No trading
29.6500 30.7600 29.6000 30.2700 266,500
30.2700 30.7600 29.0500 29.2100 347,200
29.2900 30.8900 29.0000 30.4300 701,400
Weekend
Weekend
30.0100 30.5600 29.1900 29.3500 1,463,000
29.0900 30.2700 28.3600 29.8600 795,900
29.4100 29.9500 28.1500 28.3300 439,700
26.9200 29.7250 26.0300 29.3200 932,300
27.5600 27.9450 26.6750 27.2000 1,173,500
Weekend
Weekend
28.0000 28.2500 26.7800 27.1400 305,400
28.7200 29.5100 27.1600 27.4700 661,700
28.3700 29.5500 27.9300 28.6700 342,300
28.7300 29.1700 27.9900 28.3650 403,400
28.0300 29.5000 27.9100 28.9700 345,100
Weekend
Weekend
27.8200 28.4250 27.0000 27.7500 399,900
26.6900 28.4500 26.6900 27.7400 568,500
25.0100 27.1500 24.9400 26.9700 497,300
29.6100 29.8900 24.6100 25.0100 839,100
28.3200 29.0800 28.0700 28.9800 418,300
Weekend
Weekend
28.1400 28.8900 28.0600 28.6000 145,000
No trading
29.1200 33.0000 27.8950 28.0000 509,400
26.2200 29.2900 25.8350 28.8300 683,400
25.3500 26.9940 25.3180 26.0500 1,256,800
Weekend
Weekend
24.7100 26.1000 24.1200 25.5500 384,500
25.3700 26.1900 24.7500 24.9600 402,300
25.3100 25.7950 24.1000 24.9400 422,200
26.2000 26.2000 25.0700 25.5600 585,000
24.3900 26.1500 24.1350 25.7000 527,500
Weekend
Weekend
23.0800 25.1000 23.0100 24.5300 801,800
23.5200 23.9900 22.9850 23.3400 429,900
23.7400 24.9500 23.2200 23.7200 476,600
23.3100 24.8000 22.8900 23.7800 215,000
23.5200 23.8700 22.5900 23.5000 490,500
Weekend
Weekend
23.6400 23.6400 21.9800 22.9600 271,700
24.0000 24.5800 23.0300 23.6600 289,400
25.4400 25.6500 23.6620 23.9700 234,600
6 · S-3ASR Pre-market · 07:37 ET S-3ASR ↗ 5 · 10-Q Pre-market · 07:10 ET 10-Q ↗ 4 · 8-K Pre-market · 07:05 ET 8-K ↗
24.2700 25.5650 24.0220 25.0400 342,700
25.9200 26.2200 24.7600 25.0200 316,700
Weekend
Weekend
25.7000 26.2500 25.4800 25.8500 215,100
23.9300 26.9000 23.9300 25.7700 352,900
24.8200 25.3300 23.9500 24.1900 197,900
23.5000 25.0900 23.5000 24.8400 418,000
21.9700 24.0000 21.8900 23.5800 413,900
Weekend
Weekend
21.4500 22.1400 21.4400 21.8600 186,200
22.1200 22.4200 21.0200 21.1300 241,400
22.2200 22.6200 21.9000 22.1500 450,400
23.0300 23.0300 22.1400 22.3300 475,300
21.3700 23.3400 21.1700 23.0500 787,800
Weekend
Weekend
21.8600 22.1500 20.6500 20.9700 370,900
21.7900 22.3900 21.3900 22.2800 397,400
20.1200 21.8700 20.1200 21.6900 477,900
20.6500 20.6500 19.6300 19.9800 261,700
19.7900 20.3100 19.5600 20.0800 218,200
Weekend
Weekend
19.8000 20.6800 19.4600 19.6200 271,800
18.9000 20.0900 18.6100 19.7900 636,400
18.8800 19.3000 18.7200 18.9200 328,400
18.7700 18.9600 18.1750 18.6700 190,100
18.7200 19.4400 18.7200 18.9700 335,300
Weekend
Weekend
18.6000 19.0600 18.6000 18.6300 239,500
18.6900 19.0100 18.3700 18.5900 336,900
18.6700 19.0000 18.0500 18.6300 327,800
17.3400 19.2300 17.1400 18.8100 783,000
17.2300 17.8100 17.0600 17.3400 208,400
Weekend
Weekend
16.3500 17.3200 16.2700 17.2600 254,300
16.6000 16.6300 16.0200 16.3100 171,300
16.2500 16.7800 16.1950 16.7500 294,700
16.5000 16.7900 16.1400 16.2800 190,400
16.4000 16.9800 15.9950 16.6500 322,100
Weekend
Weekend
17.4100 17.5900 16.1600 16.3800 2,447,200
16.2200 17.3950 16.1600 17.2700 342,800
17.3300 17.7800 15.5500 16.0200 540,000
16.7800 17.9700 16.6100 17.3500 593,400
17.8300 18.0000 16.7900 16.7900 374,000
Weekend
Weekend
18.0000 18.1100 17.5400 17.5700 282,400
17.7500 18.1800 17.4700 17.9200 305,300
18.2100 18.7100 17.0200 17.8000 526,200
18.7200 18.9400 17.9800 18.2400 373,700
20.0800 20.3150 18.6700 18.7300 600,700
Weekend
Weekend
19.8100 20.4200 19.0900 19.9700 556,200
20.0100 20.2800 18.5700 19.6800 563,600
20.9400 21.0300 19.5800 20.0000 970,100
16.8650 20.3800 16.6600 20.2600 2,191,700
3 · 8-K Pre-market · 08:38 ET 8-K ↗
No trading
Weekend
Weekend
16.9100 17.2200 16.3700 17.1300 305,700
16.8300 17.2000 16.4150 16.7600 444,400
17.3000 17.4250 16.6600 16.7000 254,200
16.9300 17.7800 16.9300 17.3000 356,200
17.6000 17.6000 16.5550 16.7300 215,700
Weekend
Weekend
17.8300 18.4800 17.5400 17.6300 289,100
16.0700 17.9800 16.0200 17.7400 421,900
16.7100 17.1700 16.3400 16.3600 378,900
17.9200 18.2250 16.5000 16.9000 507,900
18.9300 19.3700 17.6700 18.0200 394,800
Weekend
Weekend
18.6800 19.2750 18.1500 18.9300 424,800
18.4300 18.9500 16.8000 18.6200 525,600
17.5100 18.7000 17.0540 18.5600 557,900
16.9700 17.8200 16.6200 17.5000 290,400
16.0000 16.6200 15.6400 16.5900 1,453,400
Weekend
Weekend
15.8300 16.0000 15.1800 16.0000 214,800
17.0600 17.5710 15.8050 15.8400 371,700
15.1900 16.8000 15.0500 16.7200 366,700
2 · 10-Q Pre-market · 07:12 ET 10-Q ↗ 1 · 8-K Pre-market · 07:05 ET 8-K ↗
15.6600 16.0600 15.4450 15.5000 359,600
15.5900 15.8750 15.0400 15.6100 410,300
Weekend
Weekend
14.7800 15.5950 14.2100 15.5400 514,100
15.2500 16.1500 15.0150 15.3100 568,000
14.1300 15.4700 13.9900 15.1900 868,500
13.9900 14.6300 12.9500 13.9700 469,200
13.7300 15.2700 13.5900 14.3400 760,500
Weekend
Weekend

Announcement Events

Each title opens the filing on the SEC website. Registered users can summarise the filing and up to seven relevant exhibits linked within the same SEC submission.

17 8-K 8-K (opens SEC filing in a new tab) After-hours · 16:05 ET Summarise
16 10-Q 10-Q (opens SEC filing in a new tab) Pre-market · 07:10 ET Summarise
15 8-K 8-K (opens SEC filing in a new tab) Pre-market · 07:05 ET Summarise
14 DEFA14A DEFA14A (opens SEC filing in a new tab) After-hours · 16:10 ET Summarise
13 DEF 14A DEF 14A (opens SEC filing in a new tab) After-hours · 16:05 ET Summarise
12 8-K 8-K (opens SEC filing in a new tab) After-hours · 17:09 ET Summarise
11 424B5 424B5 (opens SEC filing in a new tab) After-hours · 17:05 ET Summarise
10 10-K 10-K (opens SEC filing in a new tab) After-hours · 16:04 ET Summarise
9 8-K 8-K (opens SEC filing in a new tab) Pre-market · 07:05 ET Summarise
8 8-K 8-K (opens SEC filing in a new tab) Pre-market · 09:17 ET Summarise
7 8-K 8-K (opens SEC filing in a new tab) Pre-market · 06:38 ET Summarise
6 S-3ASR S-3ASR (opens SEC filing in a new tab) Pre-market · 07:37 ET Summarise
5 10-Q 10-Q (opens SEC filing in a new tab) Pre-market · 07:10 ET Summarise
4 8-K 8-K (opens SEC filing in a new tab) Pre-market · 07:05 ET Summarise
3 8-K 8-K (opens SEC filing in a new tab) Pre-market · 08:38 ET Summarise
2 10-Q 10-Q (opens SEC filing in a new tab) Pre-market · 07:12 ET Summarise
1 8-K 8-K (opens SEC filing in a new tab) Pre-market · 07:05 ET Summarise